Point-sink DNA Shearing Device Stanford Reference: S95-048 Abstract Stanford researchers have developed a new method and apparatus for shearing polynucleotides. The device can shear both double (ds)- and single-stranded (ss) polynucleotides and produces a defined size distribution of fragments, with a selected mean size ranging between 200 and 20,000 for ds polynucleotides and half those values for ss polynucleotides. This technology improves upon most current methods for random DNA fragmentation by creating randomly cleaved and efficiently clonable fragments that reproducibly are small in size and fall within a narrow range in size. Applications Polynucleotide preparation for molecular cloning, sequencing, hybridization Advantages Simple operation Reproducible Produces small size fragments Requires small sample volume (to 100 microliters) Yields narrow range of fragments (within a factor of 2) Publications Issued Patent: 5,846,832 Innovators & Portfolio Scott Hunicke-Smith    Peter Oefner   more technologies from Peter Oefner » Patent Status Issued: 5,846,832 (USA) Date Released: 11/03/2009 Licensing Contact Gregg Kyle, Licensing Associate gregg.kyle@stanford.edu 650 725 3476 You must be a registered user in order to request more information on technologies. If you are already registered, please login.        Recently Viewed... S95-048 Point-sink DNA Shearing Device S95-024 Detection of DNA Heteroduplices by Denaturing High Performance Liquid Chromatography S97-248 Human Y Chromosome Specific Single Nucleotide Polymorphisms