Bioluminescence Regenerative Cycle (BRC) for Nucleic Acid Quantification Stanford Reference: S01-084 Abstract This invention provides an accurate method for detecting and qualifying target analytes. The presence of nucleic acid results in emission of light by bioluminescence regenerative cycle (BRC). The comparison of the total number of photons accumulated in different interval with the background photon emission determines the number of target nucleic acids. The target nucleic acid may be covalently or non-covalently bonded to another molecule such as a protein. The detection of the attached nucleic acid can provide indirect quantification of attached molecules. Applications Medical Forensic Epidemiological Public health Biological warfare Advantages Higher detection sensitivity compared to existing method. Quantification of any atom, molecule, complex aggregate that is attached to the target nucleic acid. Publications Hassibi A, Contag C, Vlad MO, Hafezi M, Lee TH, Davis RW, Pourmand N., Bioluminescence regenerative cycle (BRC) system: theoretical considerations for nucleic acid quantification assays. Biophys Chem. 2005 Aug 1;116(3):175-85. A. Hassibi, T. H. Lee, R. W. Davis, and N. Pourmand, Bioluminescence Regenerative Cycle (BRC) System for Nucleic Acid Quantification, Proc. of SPIE, Vol. 4966, pp. 65-75, (2003). Web Site Stanford Genome Technology Center Innovators & Portfolio Arjang Hassibi    Nader Pourmand   more technologies from Nader Pourmand » Patent Status Issued: 7,141,370 (USA) Date Released: 01/16/2004 Licensing Contact Linda Chao, Senior Associate linda.chao@stanford.edu (650) 725-9408 You must be a registered user in order to request more information on technologies. If you are already registered, please login.        Recently Viewed... S01-084 Bioluminescence Regenerative Cycle (BRC) for Nucleic Acid Quantification